00:00:10: Cybernetics and tissue, how an algorithm measures evaluates and supports regulation with microcurrents.

00:00:18: And light!

00:00:19: With that a very warm welcome to the new podcast from LuxaMate GMBH.

00:00:26: My name is Patrick Waliczek.

00:00:28: In this episode we are going do deep dive into cybernetics and feedback processes actually offer the possibility to control and regulate complex systems with physiology, and biochemistry.

00:00:51: Yes!

00:00:51: And then of course how the LUXA made algorithm uses these principles in practice... ...how it measures evaluates.. ..and how it dynamically regulates the dose of microcurrent & LED light.

00:01:07: Of course, a quick disclaimer here as well because we are talking about medical microcurrent therapy meaning the application for professional users like therapists and doctors.

00:01:19: Of course patients are also welcome to listen to our podcast but the actual practical tips and recommendations of course aimed exclusively at these professionals who have to consider the application within the framework of the medical device operator ordinance.

00:01:39: So, but very importantly by the end of this episode you'll have a very clear picture what we measure why we measure how we measure and how transport ion flows and ATP coupled processes help to bring about a sustainable steady state.

00:02:00: that is after all.

00:02:06: Now let's dive in and we'll start with cybernetics, meaning the control loop.

00:02:11: Pushing the button if you will!

00:02:13: What does Cybernetics mean?

00:02:15: Cybernetx means We work With feedback.

00:02:18: The human organism is an open system.

00:02:21: It continuously exchanges energy And substances with the environment.

00:02:27: Blood flow Lymphs Ion channels Hormones Autonomic nervous systems These are all control loops.

00:02:34: They have certain set points, they have certain measured variables but also have certain manipulated variables.

00:02:40: and therapy in a cybernetic system ultimately follows three steps measure evaluate and regulate.

00:02:47: And that's exactly what we've been doing with the Luxembourg application since yes Since twenty ten to be precise We started back then with the Luxembourg HD-One Thousand which was followed by the HD-Two Thousand, HD-Three Thousand and now The Third Version.

00:03:07: So we record electrical response patterns of the tissue classify them physiologically and adjust the stimulation parameters accordingly at short intervals.

00:03:18: And that's how guessing parameters becomes a guided intervention because we always have the feedback of the tissue to guide us.

00:03:28: To put this into a bit more context, We need to discuss a few terms from yes physics biophysics whatever because they play an extremely important role in understanding The background both scientific and technical.

00:03:44: Specifically I'd like to talk about the terms entropy enthalpy and free enthalpy And I want to try make this somewhat understandable because the terms sound, yes very academic at first but they are actually extremely useful clinically.

00:04:01: Specifically i'd like talk about the term entropy enthalpy and free-enthalpy .And I wanted tried to make it somewhat understandable beacuse the terms sounds yes very acedemic at first ,but they're actually extremely usefull clinically.

00:04:15: Let's start with enthalpy.

00:04:17: Enthalpy has a symbol H And is roughly the, yes heat and energy content of a system.

00:04:24: In tissue this is reflected in blood circulation temperature fluid distribution.

00:04:40: Finally, we have free enthalpy which is delta G. And that tells us whether a process can occur spontaneously meaning it runs on its own or driven externally.

00:04:49: and in the formula for example delta G if you take delta G equal to delta H minus T which is temperature times delta S. Let's apply this now.

00:05:04: It sounded relatively abstract, of course But let's apply these to tissue.

00:05:09: when we have acutely inflamed Tissue This is actually often exothermic that means it's warm its hyperemic Its edematous and in this case the H meaning hs high And the s is high.

00:05:19: metaphorically too much flow but two little order at the same time.

00:05:23: yes In the overall construct?

00:05:26: Let's look at the opposite.

00:05:27: We have chronically rigid tissue.

00:05:29: then we have That's more endothermic cool, poorly perfused.

00:05:34: It's more viscoelastic so rather tough.

00:05:37: there we have a low H and a low S which in turn means We Have Too Little Flow And The Energy Is So To Speak Stuck In The Tissue.

00:05:47: Why is This Important?

00:05:49: That'S A Very Important Aspect Of Course Because Microcurrent Therapy Doesn'T Work Through.

00:05:56: Yes Let'S Call It Contraction Controlled Or Stimulus Transmission Blocking Effects but rather regularly on transport, ion flows membrane potential and ATP coupled processes.

00:06:12: And these react completely differently to the same dose depending on the initial state... ...and that's why it is also yes I don't want to say pointless.. ..but thats why its important to use a feedback controlled method because These states are virtually unmeasurable from the outside.

00:06:34: And we offer these measurement methods with the looks I made to generate this feedback and determine the dose, therefore measure first and then dose.

00:06:47: now let's come to the cellular basis.

00:06:50: i think that's also a very important aspect.

00:06:52: We've talked about The cellular stories in the past In training sessions or of course in various podcasts quite a few times.

00:07:00: And let's look at the ion gradient, the membrane potential and ATP of course.

00:07:05: Every cell maintains a certain iron gradient high potassium intracellularly high sodium and chloride extracellulary but that costs ATP.

00:07:17: so it ultimately costs energy because the Na plus slash K plus ATPase pump is permanently pumping against the gradient.

00:07:29: Yes, membrane potential which if you look at it closely is ultimately the working language of the cell so it controls.

00:07:37: The channels that transporters the receptors the enzyme complexes volume and off course the pH situation in the tissue?

00:07:46: In this context ATP yes let's call it energy currency.

00:07:52: as I said we've talked about this often in past.

00:07:55: ATP is the energy currency produced mainly in mitochondria by the respiratory chain, pre-damaged tissue or overloaded tissue usually has less ATP.

00:08:08: Thus a disrupted transport is more prone to edema and of course has increased nociception.

00:08:16: And this exactly where we start with targeted medical microcurrent therapy.

00:08:24: We influence electrical boundary conditions if you will which means we influence ion movement and the electro-osmotic flows are thereby facilitated, And all ATP dependent processes can be regulated or coupled with this.

00:08:42: That is I think one of aspects that also explains.

00:08:46: This has also been shown by various studies.

00:08:49: I'd just like to mention Cheng et al regarding ATP production, who themselves conducted studies and investigations with Schoenfelder & Wetzel et al that simply show we can dramatically increase cell vitality in cell regeneration with this.

00:09:04: but now of course the opposite question why so little current one might argue meaning microcurrent right?

00:09:11: In the thousandth or millionth of an ampere range can work so well here.

00:09:18: And we have to look at Aztumian et al, he wrote about electroinformational coupling meaning electroconformational coupling and published a paper on it many years ago.

00:09:32: because many membrane proteins are electrosensitively coupled.

00:09:37: yes that's always very interesting observation also scientifically proven even small fields meaning the smallest electrical fields in the microampere range, can shift the conformational state and thus... ...the transition probability minimally if you will.

00:09:57: like a conductor quietly setting the beat for an orchestra.

00:10:01: And the orchestra follows the beat!

00:10:06: What is the consequence of this?

00:10:08: We work if-you-will subsensorially without muscle contraction.

00:10:12: This is well known to most users of microcurrent therapy but perhaps also highly interesting for patients because it makes this procedure very, very pleasant.

00:10:22: So it doesn't hurt!

00:10:25: We don't have this uncontrollable muscle contraction that we know from classic electrotherapy.

00:10:32: The effects can therefore be described as regulatory to be emphasized and not mechanical.

00:10:40: In the end the tissue decides on hydration ions pH temperature and of course, the matrix state.

00:10:50: But now let's come to a side player in this whole situation especially what we use in medical microcurrent therapy meaning BCR biological cell regulation therapy that is so called photobiomodulation referred as co-regulator.

00:11:07: We used light therapy Within or parallel to microcurrent therapy.

00:11:12: we have a red, blue and green light here which is specifically tuned.

00:11:17: And especially with the Red Light for example modulate cytochrome C oxidase in the respiratory chain We can release NO blockages thus improve oxygen utilization at the ATP rate.

00:11:30: We also conducted investigations on this at the Fraunhofer Institute specifically with the Luxamet HD-II and were able to prove exactly these effects.

00:11:41: In practice, we use the light additively with a look-summit if you will.

00:11:46: of course The focus is on microcurrent therapy.

00:11:49: the microcurrent organizes transport and ion flows And Light If You Will opens the mitochondrial window!

00:11:57: The algorithm can thus so To Speak Coordinate & Align Both Parts Which Of Course dramatically improves the symbiotic effect.

00:12:09: Let's go a bit more concretely into Users or patients who have been treated with the therapy before know this, we have a measurement phase.

00:12:36: This means that system applies small-measurement pulses and records electrical response of tissue.

00:12:43: That's actually the whole secret!

00:12:45: So... We put pulse in and achieve resonance.

00:12:49: Many people knows from FSM frequency specific microcurrent but is only an isolated part.

00:12:56: as far frequencies are concerned Here we record the entire electrical response of the tissue over several frequencies, Over polarity and beyond that a reaction curve is created.

00:13:08: And if you look at this we see the conductivity so to speak The impedance which reflects ion mobility Hydration and matrix density.

00:13:20: At same time the reaction enthalpy To put it simply heat Or another way not just the heat but the difference between heat and rigidity, meaning the contrast in the end that reflects this so-called reaction enthalpy.

00:13:37: At the same time we have a time behavior that we also measure because we have relaxation time, saturation... ...and yes recovery capability of tissue which can be more or less measured through this And algorithm compares these patterns with certain target corridors and then selects the corresponding microcurrent parameters that is, current intensity of course voltage polarity if necessary also duty cycle etc.

00:14:11: If useful components LED light therapy photobiomodulation are adjusted you can see this in different colors for those who have already experienced or performed it The whole thing carried out measured at short intervals.

00:14:27: And if we then come back to the definition of cybernetics, yes.

00:14:31: Then We are exactly in that because this is a so-called closed loop control Loop and thus This Is The Quintessence Of It?

00:14:38: The Therapy Follows The Tissue Feedback & Not Vice versa In The Classic Microcurrent Therapy Procedures As We Also Performed Them Ourselves From Two Thousand To Twenty Ten Until The First Luxem came Onto The Market.

00:14:54: We Did That Too.

00:14:55: So We Took A State a tissue, put it in and said the tissue must now follow our specification.

00:15:04: And that is exactly the error-in-reasoning because we need the feedback... ...because the therapy MUST FOLLOW THE TISSUE AND NOT vice versa!

00:15:16: That's one of the most important points.

00:15:19: Yes from measurement to dose which ultimately is the control strategy and there are three steps carried out every time.

00:15:27: First, of course measure is the pattern rather exothermic inflammatory meaning high flow low order or Rather endothermic rigid.

00:15:35: Meaning too little flow and the energy so to speak trapped.

00:15:39: Or are there also metastable areas?

00:15:41: those certainly exist?

00:15:43: And can occur in therapy.

00:15:45: and second Evaluate what physiological goal is realistic today.

00:15:50: right that's also important to consider.

00:15:52: it's often forgotten Does transport need to be facilitated here?

00:15:56: Do we need edema drainage, do the ion flows needs to be organized?

00:16:01: or do ultimately want open the ATP window provide energy directly.

00:16:06: And third of course regulate.

00:16:08: this means algorithm doses microcurrent and light checks response curve pauses changes program.

00:16:17: now program doesn't mean therapy program but rather it's based on current intensity, polarity frequency and of course voltage.

00:16:28: As soon as the specific target corridor that is set is reached.

00:16:32: yes so that means we try to trigger the processes in a targeted manner through small impulses.

00:16:40: instead of following the motto more is better.

00:16:44: let's translate this bit more into clinical patterns.

00:16:50: Let's look at acute inflammation, irritation for example bursitis or tendonitis.

00:16:55: What are the clinical signs?

00:16:56: We have heat we have swelling... ...we have tenderness and painful movements.

00:17:01: And in terms of thermodynamics.. ..we have two things!

00:17:04: A high H and a high S. That means that our objective is to channel the flow

00:17:15: i.e.,

00:17:16: support electro-osmotic drainage and simply modulate no-ceception.

00:17:23: Practically speaking, we make sure that replace the electrodes.

00:17:27: if we assume a classic adhesive electrode approach basically along drainage pathways not directly on pain then do this subsensorially for twenty to thirty minutes at short intervals in first week.

00:17:44: it makes sense especially with acute cases.

00:17:48: Yes, short term meaning to intervene at relatively short intervals.

00:17:53: And with that we are.

00:17:55: yes if you will actively assistive with small amplitudes mobilizing the course in the end.

00:18:02: so right?

00:18:03: We will see the response curves.

00:18:06: The pain will decrease parallel to the tissue feedback actually.

00:18:13: At the same time if we look at range of motion, the ROM for example that will improve.

00:18:18: let's move over to chronic rigidity.

00:18:21: lets take conditions like achillodinia old scars or myofascial imbalances.

00:18:27: what does it looks like clinically?

00:18:29: It is rather cool tough reduced conductivity fluctuating pain peaks, and looking at thermodynamics we have a reduced H. We have a reduce S so too little flow and colloquially speaking trapped energy.

00:18:48: what is the therapeutic goal in the end?

00:18:51: We want to increase order open microcirculation change matrix viscosity And simply re establish or reset the ion flows if you will.

00:19:05: This also means we need series with longer stimulation times and here it makes sense of course to place electrodes along the functional chains, that is origin insertion fascial lines.

00:19:19: And yes in post-session loading We should make sure thereby improving the glides, so to speak in relation to muscles and thus we gain a certain dynamic recovery capability relatively quickly.

00:19:34: This also increases clinical resilience from session-to-session and decreases irritability.

00:19:41: this means there are interesting studies on these.

00:19:44: I've done a podcast about it that specifically combination of microcurrent and manual therapy, osteopathic chiropractic techniques is highly recommended because we see here.

00:19:56: And we conducted a study ourselves in twenty ten.

00:20:00: this was postoperative randomized patient blinded study.

00:20:04: patients after knee arthroplasty especially regarding function resilience decreasing irritability were actually able to achieve significant results.

00:20:17: that's just one example of how important combination therapy is here.

00:20:24: Let's move on to the next clinical point, let's look at postoperative early rehabilitation.

00:20:30: for example yes shoulder after rotator cuff surgery and here we also have pain swelling tendency protective guarding and Yes, preserve the so-called gliding planes at the end of day.

00:20:50: And here too or specifically it should be applied locally to improve functional resources increase ROM and thus also yes the electromatabolic target curve simply to increase or improve.

00:21:11: Here two of course or here specifically it to improve functional resources, increase ROM and thus also yes the electrometabolic target curve simply too.

00:21:24: Increase or improve?

00:21:27: And then we also have a point of course an important aspect athletic recovery.

00:21:30: in there We also have the problem... ...we have a lactate metabolite problem that needs to be broken down or cleared here.. ..we have the problems of micro-circulation.... ....we have an autonomic rebalance that you can perform And with this, we actually have to apply the recovery sessions immediately post-exercise over a large area.

00:21:49: If you're talking about electroplacement again... ...we should of course work on our larger areas here and always LED light therapy.

00:21:55: in the past has proven very positive And approximately if you take the pre-mode before competition, before training we are at about twenty to thirty minutes in competition mode also logically in daily mode which yes and of course today leads a faster feeling of freshness better subsequent performance but also better rehabilitation or recovery.

00:22:16: We also conducted investigations on this quite few years ago with professional boxer Robert Stieglitz where he investigated with team sports scientists how his recovery individual feeling after training changes, especially.

00:22:30: After hard interval training sessions with and without microcurrent And I've already talked about this in the podcast.

00:22:37: it is de facto The case that we were able to record a significant improvement in performance Especially at the anaerobic threshold.

00:22:44: We have a faster decrease in lactate.

00:22:48: Personal opinion was simply that he feels recovered faster and that's simply shows.

00:22:53: That the topic works very, very well also in sports performance enhancement?

00:23:01: Yes Let's look a bit deeper into the mechanisms.

00:23:03: I think that's also a big topic for many.

00:23:05: Many are familiar with or go Into the field of frequency therapy.

00:23:09: there is frequency specific microcurrent therapy only see the frequencies.

00:23:14: yes let's Look at it deeper into The Mechanisms.

00:23:16: i Think thats Also A Big Topic For Many.

00:23:17: Many Are Familiar With Or go into the field of frequency therapy, that is frequency specific microcurrent therapy and only see the frequencies.

00:23:26: But perhaps we should also consider things like electro diffusion and electro osmosis here because these are things that cannot be argued away in Frequency Specific Microcurrent Therapy Because These Are Things That Simply Arise From The Current Itself Regardless Of The Frequencies And I Think Thats Why Its Also Important To Look At This in electrical fields, facilitated and transduced along charged loads.

00:23:48: And that is particularly relevant for example for edema management.

00:23:53: then we have endogenous DC meaning direct current currents if you look at them in injured tissue these are so-called currents of injury which has been described by Robert Obecker who also cited a lot on this field And these can simply have a supportive effect in representing the conduction gradients for cell migration, and let's also look at the matrix interaction.

00:24:18: The extracellular matrix is a charged hydrogel if you will.

00:24:23: electrical fields load or influence integrin bonds and the cytoskeleton, that plays an extremely important role especially in mechanotransduction.

00:24:36: And thus we are also in microcurrent therapy because we apply it externally.

00:24:40: That's why yes this DC field applied from outside is a very-very important parameter which initially has nothing directly to do with frequencies but purely with weak electrical fields.

00:24:55: If you look a bit closer, there is of course also this autonomic coupling because we have improved microcirculation and modulated nosyception.

00:25:06: This reduces the sympathetic load and promotes parasympathetic rebalance And that it totally important not only for the healing process but I think everyone who's active in sports field stress-field burnout prevention, et cetera knows that we really have a very important aspect here.

00:25:24: That we can address with microcurrent therapy which is really important and right in the area.

00:25:31: Yes regarding practical guidelines let's look at that.

00:25:34: The dose of microcurrent therapies so how it becomes if you will consistent?

00:25:42: Microcurrent Therapy is subsensorial.

00:25:44: We've already talked about this.

00:25:47: We have certain windows that we can open, yes to influence inflow and outflow pathways so To influence them.

00:25:58: And thus really having an impact in the short term on acute and often also on chronic longer Serial problems.

00:26:08: It is fundamentally important regardless of whether we are talking about a cute chronic etc.

00:26:13: Of course hydration drinking enough because without water there is no transport.

00:26:19: That's accordingly totally important and we always say that in all training sessions, a certain hydration of the patients.

00:26:31: Then of course we can also talk about certain co-therapies.

00:26:34: I mentioned earlier osteopathy, chiropractic manual therapy active training totally important respiratory therapy.

00:26:42: Yes Also a really important yes co therapist in the context of microcurrent therapy.

00:26:48: and Of course i would like to address the topic of clinical hypnosis not least for personal reasons.

00:26:55: together with dr.

00:26:56: Schellenberg I have already been able to train some therapists and doctors in clinical Hypnosis, And that is really an excellent combination therapy Not only with cybernetic microcurrent therapy but also generally with microcurrent Therapy.

00:27:14: yes documentation Is also a topic.

00:27:18: It is of course important that we use a certain form of documentation and here, We have the advantage with the Look Summit.

00:27:24: That patient management system provides documentation for response curves from therapy where the reaction enthalpy, if you will is also recorded.

00:27:38: And that is a form of quality assurance.

00:27:40: and it's important to have classic documentation in first place but can really display measured values curves or images.

00:27:55: Before we finish, I would like to address a few misunderstandings briefly and clearly because these are Misunderstandings that arise in my daily work during daily calls from interested therapists and doctors From customers but of course also a lot from patients.

00:28:11: Let's start with the first one.

00:28:13: More current helps more Of course.

00:28:16: a clear no.

00:28:17: We control loops With microcurrent therapy.

00:28:21: That is why it so pleasant or to put it another way, not unpleasant.

00:28:26: We don't have this muscle twitching This contraction...this pain that occurs with therapy because we really try to control the whole thing sub-sensorially yes and intervene in metabolism Yes!

00:28:45: The next point would be a fixed protocol is always enough And I say very clearly no It's simply not always enough.

00:28:52: and resonance meaning the resonance effect.

00:28:55: If it's not measured, then its relatively difficult to perceive a resonance at all.

00:29:00: because how else am I going to perceive if i can't measure?

00:29:04: And How Am I Going To Adjust Or Change Something If I Haven't Measured It.

00:29:07: So No!

00:29:09: The states change and here is totally important.

00:29:12: that dose means also composition of protocol follows measurement.

00:29:17: thus follow tissue.

00:29:18: Important I think it's also logically physical medical technical.

00:29:23: in end Microcurrent replaces movement.

00:29:26: That is also such a yes, A piece of fake news if you will know.

00:29:31: microcurrent opens the window The window energetic window the metabolic Window and the movements stabilizes itself through this gain from opening the window.

00:29:45: Yes What does the algorithm actually take off your hands?

00:29:48: if we refer to the HD two thousand plus again?

00:29:50: what Does it Actually Take Off Your Hands in Everyday Life?

00:29:53: Yes, In The End It's Like This.

00:29:55: The Adaptive Programs Follow The Tissue Response.

00:29:57: That Means More Transparency.

00:29:59: The Course Becomes More Visible Not Only For You As The User But Also for The Patients For The Team.

00:30:06: you Have Better Use Of Time While You Are Mobilizing and Guiding.

00:30:10: The System Maintains.

00:30:12: that's the beauty of being able to combine it directly with so-called metabolic target corridor.

00:30:18: And, I would like to conclude and give you three core sentences to take away.

00:30:26: first tissue is a dynamically open system.

00:30:31: disorders are always thermodynamic shifts not broken parts because which cell at end of day is actually sick voluntarily?

00:30:41: That will be opposite question.

00:30:43: So, we work with open thermodynamic systems and anyone can read about that in biology or biophysics.

00:30:50: That is a fact!

00:30:53: Microcurrent works regularly... ...that's the second key point I would like to share.

00:31:00: Transport, ion flows & ATP production which achieve great effect on small impulses.

00:31:13: our algorithm which measures, evaluates and regulates in a loop.

00:31:18: This is how the therapy is guided instead of having to more or less guess it using fixed protocols!

00:31:28: And with that we are now at the end of this episode.

00:31:32: I hope i was able.

00:31:33: It is indeed a difficult topic.

00:31:36: For example, this coming October for those who listen to the podcast a bit later it's currently September twelfth twenty-twenty five and we are starting a seminar series in mid-October namely A Series on The Basics of Microcurrent Therapy with our doctor and orthopedist Dr.

00:31:53: Voracek who has spent a very, very long time dealing specifically with this electro-confirmational coupling and ultimately developed the algorithm for microcurrent therapy from it.

00:32:06: He had been user himself since two thousand.

00:32:09: so now for twenty five years he's used of microcurrent therapies and logically knows his way around all areas regarding frequencies polarities current intensities and we have him as a specialist speaker live here with us in Kassel again, in October.

00:32:26: And I think that we've already almost reached the maximum number of participants for this seminar!

00:32:32: Then comes Florian Schöning, an alternative practitioner, physiotherapist or osteopath expert on frequency-specific microcurrent therapy.

00:32:43: He talks about FSM according to Dr Carol MacMacon who is trained instructor himself by Dr.

00:32:51: Carol MacMacon and simply passes on his knowledge to therapists and doctors specifically related to the FSM area.

00:33:00: you can find all of this in our show notes via the link that takes you directly to a blog post of ours, there Yes, so in short I would like to say thank you very much for staying with us.

00:33:15: For So long even if this episode might not have been so easy In terms of wording and the topic.

00:33:20: but i believe it is important And right To address these topics here as well?

00:33:39: very, very important and right.

00:33:42: Yes!

00:33:42: And in that sense I say thank you very much.